Emerging Intracellular Electrical Phenomena: Implications for Paradigm Shifts in Biological Chemistry Research

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Summary of the article  The human body depends on electrical charges for many biological processes, including brain activity and nerve impulses. Previously, it was believed that cellular membranes were necessary to create an electrical charge imbalance. However, recent research from Stanford University has shown that a similar electrical imbalance can exist between microdroplets of water and air. Now, researchers from Duke University have discovered that these types of electric fields also exist within and around biological condensates, a type of cellular structure. These structures form compartments inside the cell without needing the physical boundary of a membrane. The researchers discovered that when environmental conditions are right, a previously unknown phenomenon occurs in these biological condensates, which creates a redox reaction that produces tiny amounts of hydrogen peroxide. This discovery could change the way researchers think about biological chemistry and provide a clu

Back pain and good body posture


Back pain is one of the most common cause of disability worldwide. It is a common complaint that most people have at some point in their lives. It frequently first appears throughout adolescence and grows more prevalent as people age. Back pain can become persistent, incapacitating, and distressing for 25% of persons who experience it. It may limit a person's capacity to engage in daily tasks, physical activity, and employment. Back discomfort is frequently made worse by actions including sitting, standing, bending, and lifting. It's a widely held concept that maintaining "excellent" posture is crucial for both preventing and treating back pain as well as shielding the spine from harm.





It's a widely held concept that maintaining "good" posture is crucial for both preventing and treating back pain as well as shielding the spine from harm. A common definition of good posture is sitting "upright," standing "tall and aligned," and lifting with a squat technique and "straight back." On the other hand, it is generally advised against "slumping," "slouching," and lifting while hunched over or with a "round back." Both those with and without back pain share this opinion, as do medical professionals working in occupational health and primary care settings. Surprisingly, there is little proof that "good" posture and back pain are strongly correlated. 


People's perceptions of "good" posture are a result of a mix of incorrect assumptions and social desirability. Systematic reviews, which analyze several research in one area, have indicated that worker ergonomic interventions and tips for manual workers on the proper lifting posture have not decreased work-related back pain.


Several studies were conducted to find the relationship between the good body posture and the back pain problems. From these studies it was clear that lull sitting or non natural standing postures in the teenage or the young kids may be linked to the predicted future back pain. These results are in line with comprehensive evaluations that identified no discernible variations in standing or sitting posture between adult populations with and without back pain. There are many distinct spine positions that people choose, and no particular position completely shields a person against back pain. Both upright and slumped postures can cause back discomfort in individuals.


There is also a lack of evidence supporting widely accepted occupational health guidelines about "safe" or excellent back postures while lifting. There is no proof, according to a systematic review, that lifting with a round-back position causes or foretells back pain. In a recent lab investigation, it was discovered that individuals without back discomfort who had worked manually for more than five years were more likely to lift objects with a hunched, round-back posture. Manual workers with back pain, in contrast, tended to adopt a more squat lift while maintaining a straighter back. In other words, those who have back pain tend to adhere to "good" posture advice, whereas those who do not lift in a "good" manner do not experience increased back discomfort. A modest study found that once patients with incapacitating back pain recovered, they tended to become less protective and generally strayed from the "excellent" posture recommendations.


There is no proof that only "good posture" can prevent or lessen back pain. Since everyone's spines are unique, posture depends greatly on the individual. Movement is crucial for the health of your spine, so learning to switch up your posture and find comfortable positions that you can hold will likely be more beneficial than stubbornly maintaining one "good" posture. Even though back pain can be severe and debilitating, 90% of patients report that it is not caused by pathology or observable tissue damage.

Back pain can be like a severe headache when there is no damage, but it can also be like a sprain when there are awkward, sudden, heavy, or unaccustomed loads on our backs. The following situations illustrate how people are more susceptible to back discomfort when their health is at risk: feeling tense, unhappy, or worn out, sleeping poorly, and being less active.

If a person overprotects their back, overworries and fears their back pain, avoids movement, physical activity, job, and social engagement, or does any of the following, their back discomfort is more likely to last.

Back discomfort may be brought on by pathology in a small percentage of people (1–5%), such as a fracture, cancer, infection, or nerve compression (the latter is associated with leg pain, and a loss of muscle power and sensation). When this happens, get medical help. 90 percent of the time, back pain is brought on by a sensitivity of the back structures rather than actual tissue damage. In this circumstance, a preoccupation with maintaining "excellent" posture may divert attention from other elements that are recognized to be crucial for spine health includes 

Exercise and back relaxation, maintaining a healthy sleep schedule, maintaining a healthy body weight, and participating in regular physical activity of your choice can improve your confidence and keep you fit and strong for daily duties. Sometimes a professional  counseling and support are needed for this. Find relaxed, comfortable positions and change them whether you are standing or seated.

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